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產(chǎn)品規(guī)格
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BN40481R-100ul
100ul
￥2360.00
交叉反應(yīng)：Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推薦應(yīng)用：IHC-P,IHC-F,ICC,IF,ELISA
BN40481R-200ul
200ul
￥3490.00
交叉反應(yīng)：Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推薦應(yīng)用：IHC-P,IHC-F,ICC,IF,ELISA
產(chǎn)品描述
| 英文名稱 | KIF13A |
| 中文名稱 | 驅(qū)動(dòng)蛋白家族成員13A抗體 |
| 別 名 | bA500C11.2; FLJ27232; KI13A_HUMAN; KIF 13A; Kif13a; Kinesin family member 13A; Kinesin like protein KIF13A; Kinesin like protein RBKIN; Kinesin-like protein KIF13A; Kinesin-like protein RBKIN; RBKIN. |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse, Rat, (predicted: Human, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 202kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KIF13A:1501-1600/1805 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011] Function: Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenesis and cytokinesis. Mediates the transport of M6PR-containing vesicles from trans-Golgi network to the plasma membrane via direct interaction with the AP-1 complex. During melanosome maturation, required for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes by creating peripheral recycling endosomal subdomains in melanocytes. Also required for the abcission step in cytokinesis: mediates translocation of ZFYVE26, and possibly TTC19, to the midbody during cytokinesis. Subcellular Location: Cytoplasm > cytoskeleton > centrosome. Midbody. Endosome membrane. Golgi apparatus membrane. Recruited to the midbody during cytokinesis. Tissue Specificity: Widely expressed, with highest levels in heart, brain and skeletal muscle. Similarity: Belongs to the kinesin-like protein family. Contains 1 FHA domain. Contains 1 kinesin-motor domain. SWISS: Q9H1H9 Gene ID: 63971 Database links: Entrez Gene: 63971 Human Omim: 605433 Human SwissProt: Q9H1H9 Human Unigene: 94499 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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